At doses above the recommended dose range, adverse reactions were similar to those detailed in Table 1 below but generally were reported more frequently.Subjects who had successfully completed the previous doxazosin interaction study (using VIAGRA 50 mg), including no significant hemodynamic adverse events, were allowed to skip dose period 1.

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In a study of healthy male volunteers, sildenafil (100 mg) did not affect the steady state pharmacokinetics of the HIV protease inhibitors, saquinavir and ritonavir, both of which are CYP3A4 substrates.Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure.Similar effects on blood pressure were noted with 25 mg, 50 mg and 100 mg of VIAGRA, therefore the effects are not related to dose or plasma levels within this dosage range.A stronger CYP3A4 inhibitor such as ketoconazole or itraconazole could be expected to have greater effect than that seen with saquinavir.INDICATION VIAGRA (sildenafil citrate) is prescription medicine used to treat erectile dysfunction (ED).Sildenafil at recommended doses has no effect in the absence of sexual stimulation.Therefore, the use of such combinations is not recommended. 5.8 Effects on Bleeding There have been postmarketing reports of bleeding events in patients who have taken VIAGRA.

Includes: indications, dosage, adverse reactions, pharmacology and more.Metabolic and Nutritional: thirst, edema, gout, unstable diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemic reaction, hypernatremia.Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine.The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized.

Your blood pressure could drop to an unsafe level are allergic to sildenafil, as contained in VIAGRA and REVATIO, or any of the ingredients in VIAGRA Discuss your health with your doctor to ensure that you are healthy enough for sex.Pfizer Laboratories Div Pfizer Inc ---------- HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use VIAGRA safely and effectively.IMPORTANT SAFETY INFORMATION Do not take VIAGRA (sildenafil citrate) if you: take any medicines called nitrates, often prescribed for chest pain, or guanylate cyclase stimulators like Adempas (riociguat) for pulmonary hypertension.Most, but not all, of these patients had preexisting cardiovascular risk factors.If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took VIAGRA.Do not use VIAGRA for a condition for which it was not prescribed.

When VIAGRA is taken with a high fat meal, the rate of absorption is reduced, with a mean delay in T max of 60 minutes and a mean reduction in C max of 29%.In volunteers with severe renal impairment (Clcr max and AUC.

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Ask your doctor if your heart is healthy enough to handle the extra strain of having sex.Such an event may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION), a rare condition and a cause of decreased vision including permanent loss of vision, that has been reported rarely post-marketing in temporal association with the use of all PDE5 inhibitors.Following at least 14 consecutive daily doses of doxazosin, VIAGRA 100 mg or matching placebo was administered simultaneously with doxazosin.Use VIAGRA with caution in patients predisposed to priapism ( 5.2 ) Patients should stop VIAGRA and seek medical care if a sudden loss of vision occurs in one or both eyes, which could be a sign of non arteritic anterior ischemic optic neuropathy (NAION).

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Find patient medical information for Viagra oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Do not give VIAGRA to other people, even if they have the same symptoms that you have.Stop taking VIAGRA and call your healthcare provider right away if you have any sudden vision loss sudden hearing decrease or hearing loss.

The evaluation of erectile dysfunction should include a determination of potential underlying causes and the identification of appropriate treatment following a complete medical assessment.A sudden drop in blood pressure can cause you to feel dizzy, faint, or have a heart attack or stroke.

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The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range.Your doctor will start you on the VIAGRA dose he thinks is right for you.After patients have taken VIAGRA, it is unknown when nitrates, if necessary, can be safely administered.The type of adverse reactions in flexible-dose studies, which reflect the recommended dosage regimen, was similar to that for fixed-dose studies.In healthy male volunteers, there was no evidence of a clinically significant effect of azithromycin (500 mg daily for 3 days) on the systemic exposure of sildenafil or its major circulating metabolite.

Nervous: ataxia, hypertonia, neuralgia, neuropathy, paresthesia, tremor, vertigo, depression, insomnia, somnolence, abnormal dreams, reflexes decreased, hypesthesia.Rarely reported side effects include: an erection that will not go away (priapism).Study 1: VIAGRA with Doxazosin In the first study, a single oral dose of VIAGRA 100 mg or matching placebo was administered in a 2-period crossover design to 4 generally healthy males with benign prostatic hyperplasia (BPH).After either oral or intravenous administration, sildenafil is excreted as metabolites predominantly in the feces (approximately 80% of administered oral dose) and to a lesser extent in the urine (approximately 13% of the administered oral dose).The information provided in this site is intended only for healthcare professionals in the United States.Concomitant use may lead to hypotension ( 5.5 ) Decreased blood pressure, syncope, and prolonged erection may occur at higher sildenafil exposures.