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Patients whose artery blockage is severe enough to cause chest pain may be prescribed nitrates — whether in a patch, a long-lasting oral form or a fast-acting nitroglycerin pill placed under the tongue — to alleviate their symptoms.

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At issue is sudden vision loss when blood flow to the optic nerve is blocked, a condition called NAION or non-arteritic anterior ischemic optic neuropathy.

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Levitra is sold in the United States by GlaxoSmithKline PLC and Schering-Plough Corp. and overseas by Bayer AG.It may aid in the treatment of enlarged hearts that can result from high blood pressure, tests on animals indicate.

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The possibility of a link with blindness was raised publicly earlier this year, when Dr.But publicity over the FDA investigation could result in more cases coming forward, said Bazell, noting that a bigger study examining the link is needed.Pfizer shares declined Friday on the New York Stock Exchange after news of the blindness cases.

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Pfizer also said at the time that Viagra had a 68 percent worldwide market share.

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Levitra was approved in August 2003, and Cialis in November of that year.

Viagra, approved to treat erectile dysfunction, should not be used by men with heart conditions whose doctors have warned them not to have sex.Erectile Dysfunction Agents (Viagra, Levitra, Cialis, Staxyn,.The FDA has 43 reports of NAION among the impotence drug users: 38 for Viagra, four for Cialis and one for Levitra, said spokeswoman Susan Cruzan.FDA launches probe, but stresses no evidence yet Viagra, Cialis to blame.Also complicating the question: NAION is considered one of the most common causes of sudden vision loss in older Americans, and estimates suggest there are anywhere from 1,000 to 6,000 cases a year.

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